Contact sensitizers induce skin inflammation via ROS production and hyaluronic acid degradation.

<h4>Background</h4>Allergic contact dermatitis (ACD) represents a severe health problem with increasing worldwide prevalence. It is a T cell-mediated skin disease induced by protein-reactive organic and inorganic chemicals. A key feature of contact allergens is their ability to trigger a...

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Bibliographic Details
Main Authors: Philipp R Esser, Ute Wölfle, Christoph Dürr, Friederike D von Loewenich, Christoph M Schempp, Marina A Freudenberg, Thilo Jakob, Stefan F Martin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22848468/?tool=EBI