Quantification of intrinsic subtype ambiguity in Luminal A breast cancer and its relationship to clinical outcomes
Abstract Background PAM50 gene profiling assigns each cancer to a single intrinsic subtype. However, individual cancers vary in their adherence to a prototype, and due to bulk tissue sampling, some may exhibit expression patterns that indicate intra-tumor admixture of multiple subtypes. Our objectiv...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-03-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12885-019-5392-z |