Postsynaptic GABA(B) Receptors Contribute to the Termination of Giant Depolarizing Potentials in CA3 Neonatal Rat Hippocampus

Postsynaptic GABA(B) Receptors Contribute to the Termination of Giant Depolarizing Potentials in CA3 Neonatal Rat Hippocampus

During development, hippocampal CA3 network generates recurrent population bursts, so-called Giant Depolarizing Potentials (GDPs). GDPs are characterized by synchronous depolarization and firing of CA3 pyramidal cells followed by afterhyperpolarization (GDP-AHP). Here, we explored the properties of...

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Bibliographic Details
Main Authors: Ilgam Khalilov, Marat Minlebaev, Marat Mukhtarov, Elvira Juzekaeva, Roustem Khazipov
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
GABA
giant depolarizing potentials
neonatal
hippocampus
patch-clamp techniques
development
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00179/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2017.00179/full

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