Central Precocious Puberty in two Boys with Prader-Willi Syndrome on Growth Hormone Treatment

ABSTRACT: Objective: Prader-Willi syndrome (PWS) is a rare genetic neuroendocrine disorder characterized by hypotonia, obesity, short stature, and mental retardation. Incomplete or delayed pubertal development as well as premature adrenarche are usually found in PWS, whereas central precocious pube...

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Main Authors: Elena Monai, MD, Anders Johansen, MD, PhD, Erik Clasen-Linde, MD, Ewa Rajpert-De Meyts, MD, DMSc, Niels Erik Skakkebæk, MD, DMSc, Katharina M. Main, MD, PhD, Anne Jørgensen, MSc, PhD, Rikke Beck Jensen, MD, PhD
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:AACE Clinical Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2376060520300419