The p90 ribosomal S6 kinase (RSK) is a mediator of smooth muscle contractility.
In the canonical model of smooth muscle (SM) contraction, the contractile force is generated by phosphorylation of the myosin regulatory light chain (RLC20) by the myosin light chain kinase (MLCK). Moreover, phosphorylation of the myosin targeting subunit (MYPT1) of the RLC20 phosphatase (MLCP) by t...
Main Authors: | Mykhaylo Artamonov, Ko Momotani, Darkhan Utepbergenov, Aaron Franke, Alexander Khromov, Zygmunt S Derewenda, Avril V Somlyo |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3596281?pdf=render |
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