Roles for IFT172 and Primary Cilia in Cell Migration, Cell Division, and Neocortex Development

Roles for IFT172 and Primary Cilia in Cell Migration, Cell Division, and Neocortex Development

The cilium of a cell translates varied extracellular cues into intracellular signals that control embryonic development and organ function. The dynamic maintenance of ciliary structure and function requires balanced bidirectional cargo transport involving intraflagellar transport (IFT) complexes. IF...

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Bibliographic Details
Main Authors: Michal Pruski, Ling Hu, Cuiping Yang, Yubing Wang, Jin-Bao Zhang, Lei Zhang, Ying Huang, Ann M. Rajnicek, David St Clair, Colin D. McCaig, Bing Lang, Yu-Qiang Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
neocortex
IFT172
primary cilium
directed migration
corticogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00287/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2019.00287/full

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