Integrating diverse datasets improves developmental enhancer prediction.

Integrating diverse datasets improves developmental enhancer prediction.

Gene-regulatory enhancers have been identified using various approaches, including evolutionary conservation, regulatory protein binding, chromatin modifications, and DNA sequence motifs. To integrate these different approaches, we developed EnhancerFinder, a two-step method for distinguishing devel...

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Bibliographic Details
Main Authors: Genevieve D Erwin, Nir Oksenberg, Rebecca M Truty, Dennis Kostka, Karl K Murphy, Nadav Ahituv, Katherine S Pollard, John A Capra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4072507?pdf=render

Internet

http://europepmc.org/articles/PMC4072507?pdf=render

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