Decreasing α-synuclein aggregation by methanolic extract of Centella asiatica in zebrafish Parkinson's model

Objective: To observe the effects of Centella asiatica (C. asiatica) methanolic extract on α-synuclein aggregation and its expression in rotenone-exposed zebrafish. Methods: Zebrafish (Danio rerio) were exposed to 5 μg/L rotenone for 28 days and co-incubated with 2.5, 5.0 and 10.0 μg/mL of C. asiati...

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Bibliographic Details
Main Authors: Husnul Khotimah, Mulyohadi Ali, Sutiman Bambang Sumitro, Mochamad Aris Widodo
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-11-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2221169115001926