Mast Cells and Arachidonic Acid Cascade in Inflammation

Prostaglandin D2 PGD2 is a major cyclooxygenase metabolite of arachidonic acid produced by mast cells and it is released following allergen challenge in diseases, such as allergic diseases. PGD2 may act as a neuromodulator and as an allergic and inflammatory mediator. In allergic diseases, activated...

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Bibliographic Details
Main Authors: M.L. Castellani, M. Felaco, F. Pandolfi, V. Salini, D. De Amicis, C. Orso, J. Vecchiet, S. Tetè, C. Ciampoli, F. Conti, G. Cerulli, A. Caraffa, P. Antinolfi, C. Cuccurullo, P. Felaco, D. Kempuraj, P. Boscolo, G. Sabatino, Y.B. Shaik
Format: Article
Language:English
Published: SAGE Publishing 2009-09-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/1721727X0900700302