A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum

A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum

Summary: Tight coordination of gene expression in the developing cerebellum is crucial for establishment of neuronal circuits governing motor and cognitive function. However, transcriptional changes alone do not explain all of the switches underlying neuronal differentiation. Here we unveiled a wide...

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Bibliographic Details
Main Authors: Donatella Farini, Eleonora Cesari, Robert J. Weatheritt, Gina La Sala, Chiara Naro, Vittoria Pagliarini, Davide Bonvissuto, Vanessa Medici, Marika Guerra, Chiara Di Pietro, Francesca Romana Rizzo, Alessandra Musella, Valeria Carola, Diego Centonze, Benjamin J. Blencowe, Daniela Marazziti, Claudio Sette
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Cell Reports
Subjects:
alternative splicing
synaptogenesis
neuronal activity
cerebellum development
Sam68
social behavior
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720306732

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http://www.sciencedirect.com/science/article/pii/S2211124720306732

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