Aliskiren Attenuates the Inflammatory Response and Wound Healing Process in Diabetic Mice With Periodontal Disease

Aliskiren Attenuates the Inflammatory Response and Wound Healing Process in Diabetic Mice With Periodontal Disease

The aim of this study was to characterize the role of local RAS (renin–angiotensin system) in the inflammatory response of normal (N) and diabetic (D) mice with periodontal disease (PD). Diabetes Mellitus (DM) was induced by peritoneal injection of streptozotocin in Balb/c mice. PD was induced by li...

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Bibliographic Details
Main Authors: Sandra Helena Penha Oliveira, Victor Gustavo Balera Brito, Sabrina Cruz Tfaile Frasnelli, Bianca da Silva Ribeiro, Milena Nunes Ferreira, Dayane Priscilla Queiroz, Carluci Taís Beltan, Vanessa Soares Lara, Carlos Ferreira Santos
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Pharmacology
Subjects:
renin–angiotensin system
diabetes
periodontal disease
inflammation
renin
collagen
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00708/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00708/full

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