Impairment of autophagic flux promotes glucose reperfusion-induced neuro2A cell death after glucose deprivation.

Hypoglycemia-induced brain injury is a common and serious complication of intensive insulin therapy experienced by Type 1 diabetic patients. We previously reported that hypoglycemic neuronal death is triggered by glucose reperfusion after hypoglycemia rather than as a simple result of glucose depriv...

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Bibliographic Details
Main Authors: Bong Geom Jang, Bo Young Choi, Jin Hee Kim, Min-Ju Kim, Min Sohn, Sang Won Suh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3790699?pdf=render