Microdevice for directional axodendritic connectivity between micro 3D neuronal cultures

Abstract Neuronal cultures are widely used in neuroscience research. However, the randomness of circuits in conventional cultures prevents accurate in vitro modeling of cortical development and of the pathogenesis of neurological and psychiatric disorders. A basic feature of cortical circuits that i...

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Bibliographic Details
Main Authors: Yixuan Ming, Md Joynal Abedin, Svetlana Tatic-Lucic, Yevgeny Berdichevsky
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Microsystems & Nanoengineering
Online Access:https://doi.org/10.1038/s41378-021-00292-9