Control of Ion Transport by Tmem16a Expressed in Murine Intestine

Control of Ion Transport by Tmem16a Expressed in Murine Intestine

Cl– secretion by the human and murine intestinal epithelium occurs through the cystic fibrosis transmembrane conductance regulator (cftr). However, the Ca2+ activated Cl– channel Tmem16a was shown to contribute to Cl– secretion, mainly, but not exclusively, as a basolaterally located Cl– channel tha...

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Bibliographic Details
Main Authors: Karl Kunzelmann, Raquel Centeio, Podchanart Wanitchakool, Inês Cabrita, Roberta Benedetto, Tultul Saha, Kazi Mirajul Hoque, Rainer Schreiber
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Physiology
Subjects:
Tmem16a
anoctamin 1
Cl– secretion
mucus secretion
cystic fibrosis
Ca2+ signaling
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01262/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.01262/full

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