Sensitivity of yeast to lithium chloride connects the activity of YTA6 and YPR096C to translation of structured mRNAs.

Lithium Chloride (LiCl) toxicity, mode of action and cellular responses have been the subject of active investigations over the past decades. In yeast, LiCl treatment is reported to reduce the activity and alters the expression of PGM2, a gene that encodes a phosphoglucomutase involved in sugar meta...

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Main Authors: Maryam Hajikarimlou, Houman Moteshareie, Katayoun Omidi, Mohsen Hooshyar, Sarah Shaikho, Tom Kazmirchuk, Daniel Burnside, Sarah Takallou, Narges Zare, Sasi Kumar Jagadeesan, Nathalie Puchacz, Mohan Babu, Myron Smith, Martin Holcik, Bahram Samanfar, Ashkan Golshani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0235033