Angiopoietin-2 and biliary diseases: elevated serum, but not bile levels are associated with cholangiocarcinoma.

BACKGROUND:The diagnosis of cholangiocarcinoma (CC) is challenging especially in patients with primary sclerosing cholangitis (PSC) and often delayed due to the lack of reliable markers. Angiopoietin-2 (Angpt-2) has been employed as a biomarker of angiogenesis and might be involved in tumor neoangio...

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Bibliographic Details
Main Authors: Torsten Voigtländer, Sascha David, Kristina Thamm, Jerome Schlué, Jochen Metzger, Michael P Manns, Tim O Lankisch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4019663?pdf=render