Ovarian Cancer Relies on Glucose Transporter 1 to Fuel Glycolysis and Growth: Anti-Tumor Activity of BAY-876

Ovarian Cancer Relies on Glucose Transporter 1 to Fuel Glycolysis and Growth: Anti-Tumor Activity of BAY-876

The recent progresses in understanding of cancer glycolytic phenotype have offered new strategies to manage ovarian cancer and other malignancies. However, therapeutic targeting of glycolysis to treat cancer remains unsuccessful due to complex mechanisms of tumor glycolysis and the lack of selective...

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Bibliographic Details
Main Authors: Yibao Ma, Wei Wang, Michael O. Idowu, Unsong Oh, Xiang-Yang Wang, Sarah M. Temkin, Xianjun Fang
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Cancers
Subjects:
ovarian cancer
glucose transporter 1
BAY-876
glycolysis
patient-derived xenograft
Online Access:http://www.mdpi.com/2072-6694/11/1/33

Internet

http://www.mdpi.com/2072-6694/11/1/33

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