Identification of epigenetic interactions between miRNA and DNA methylation associated with gene expression as potential prognostic markers in bladder cancer

Identification of epigenetic interactions between miRNA and DNA methylation associated with gene expression as potential prognostic markers in bladder cancer

Abstract Background One of the fundamental challenges in cancer is to detect the regulators of gene expression changes during cancer progression. Through transcriptional silencing of critical cancer-related genes, epigenetic change such as DNA methylation plays a crucial role in cancer. In addition,...

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Bibliographic Details
Main Authors: Manu Shivakumar, Younghee Lee, Lisa Bang, Tullika Garg, Kyung-Ah Sohn, Dokyoon Kim
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Medical Genomics
Subjects:
Interaction between miRNA and methylation
Integrative analysis
Bladder cancer
TCGA
Online Access:http://link.springer.com/article/10.1186/s12920-017-0269-y

Internet

http://link.springer.com/article/10.1186/s12920-017-0269-y

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