Conserved strategies of RNA polymerase I hibernation and activation

RNA polymerase (Pol) I transcribes the ribosomal RNA precursor in eukaryotes. Here, the authors present three cryo-EM structure of S. pombe Pol I in different functional states among them a dimer structure and discuss conserved and organism-specific features of Pol I.

Bibliographic Details
Main Authors: Florian B. Heiss, Julia L. Daiß, Philipp Becker, Christoph Engel
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21031-8