Suppression of Laccase 2 severely impairs cuticle tanning and pathogen resistance during the pupal metamorphosis of Anopheles sinensis (Diptera: Culicidae)

Suppression of Laccase 2 severely impairs cuticle tanning and pathogen resistance during the pupal metamorphosis of Anopheles sinensis (Diptera: Culicidae)

Abstract Background Phenol oxidases (POs) catalyze the oxidation of dopa and dopamine to melanin, which is crucial for cuticle formation and innate immune maintenance in insects. Although, Laccase 2, a member of the PO family, has been reported to be a requirement for melanin-mediated cuticle tannin...

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Bibliographic Details
Main Authors: Ming-Hui Du, Zheng-Wen Yan, You-Jin Hao, Zhen-Tian Yan, Feng-Ling Si, Bin Chen, Liang Qiao
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Parasites & Vectors
Subjects:
Anopheles sinensis
Laccase 2
Phenol oxidases
Cuticle tanning
Melanization
Immunity
Online Access:http://link.springer.com/article/10.1186/s13071-017-2118-4

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http://link.springer.com/article/10.1186/s13071-017-2118-4

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