Changes in N6-Methyladenosine Modification Modulate Diabetic Cardiomyopathy by Reducing Myocardial Fibrosis and Myocyte Hypertrophy

Changes in N6-Methyladenosine Modification Modulate Diabetic Cardiomyopathy by Reducing Myocardial Fibrosis and Myocyte Hypertrophy

In this study, we aimed to systematically profile global RNA N6-methyladenosine (m6A) modification patterns in a mouse model of diabetic cardiomyopathy (DCM). Patterns of m6A in DCM and normal hearts were analyzed via m6A-specific methylated RNA immunoprecipitation followed by high-throughput sequen...

Full description

Bibliographic Details
Main Authors: Wenhao Ju, Kai Liu, Shengrong Ouyang, Zhuo Liu, Feng He, Jianxin Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
diabetic cardiomyopathy
m6A
myocardial fibrosis
FTO
myocyte hypertrophy
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.702579/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.702579/full

Similar Items