Apolipoprotein-E forms dimers in human frontal cortex and hippocampus

<p>Abstract</p> <p>Background</p> <p>Apolipoprotein-E (apoE) plays important roles in neurobiology and the apoE4 isoform increases risk for Alzheimer's disease (AD). ApoE3 and apoE2 are known to form disulphide-linked dimers in plasma and cerebrospinal fluid wherea...

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Bibliographic Details
Main Authors: Halliday Glenda M, Elliott David A, Garner Brett
Format: Article
Language:English
Published: BMC 2010-02-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/11/23