The Anti-Pseudomonal Peptide D-BMAP18 Is Active in Cystic Fibrosis Sputum and Displays Anti-Inflammatory In Vitro Activity

The Anti-Pseudomonal Peptide D-BMAP18 Is Active in Cystic Fibrosis Sputum and Displays Anti-Inflammatory In Vitro Activity

Most Cystic Fibrosis (CF) patients succumb to airway inflammation and pulmonary infections due to <i>Pseudomonas aeruginosa</i>. <i>D</i>-BMAP18, a membrane-permeabilizing antimicrobial peptide composed of D-amino acids, was evaluated as a possible antibacterial aimed to addr...

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Bibliographic Details
Main Authors: Margherita Degasperi, Chiara Agostinis, Mario Mardirossian, Massimo Maschio, Andrea Taddio, Roberta Bulla, Marco Scocchi
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Microorganisms
Subjects:
antimicrobial peptide
cystic fibrosis
<i>P. aeruginosa</i> infection
inflammation
BMAP-18
Online Access:https://www.mdpi.com/2076-2607/8/9/1407

Internet

https://www.mdpi.com/2076-2607/8/9/1407

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