Induction Phase of Spontaneous Liver Transplant Tolerance

The liver has long been known to possess tolerogenic properties. Early experiments in liver transplantation demonstrated that in animal models, hepatic allografts could be accepted across MHC-mismatch without the use of immunosuppression, and that transplantation of livers from the same donor was ca...

Full description

Bibliographic Details
Main Authors: Geoffrey W. McCaughan, David G. Bowen, Patrick J. Bertolino
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01908/full