A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA

Riboswitches consist of an aptamer domain and expression platform, which senses a signal and regulates gene expression, respectively. Here the authors show that the expression platform of a SAM-I riboswitch from the Gram-negative bacteria can sense and bind uncharged an initiator Met tRNA to control...

Full description

Bibliographic Details
Main Authors: Dong-Jie Tang, Xinyu Du, Qiang Shi, Jian-Ling Zhang, Yuan-Ping He, Yan-Miao Chen, Zhenhua Ming, Dan Wang, Wan-Ying Zhong, Yu-Wei Liang, Jin-Yang Liu, Jian-Ming Huang, Yun-Shi Zhong, Shi-Qi An, Hongzhou Gu, Ji-Liang Tang
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16417-z