Sepsis enhances epithelial permeability with stretch in an actin dependent manner.

Ventilation of septic patients often leads to the development of edema and impaired gas exchange. We hypothesized that septic alveolar epithelial monolayers would experience stretch-induced barrier dysfunction at a lower magnitude of stretch than healthy alveolar epithelial monolayers. Alveolar epit...

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Bibliographic Details
Main Authors: Taylor S Cohen, Brian C DiPaolo, Gladys Gray Lawrence, Susan S Margulies
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3378620?pdf=render