Interactions between the discoidin domain receptor 1 and β1 integrin regulate attachment to collagen

Interactions between the discoidin domain receptor 1 and β1 integrin regulate attachment to collagen

Summary Collagen degradation by phagocytosis is essential for physiological collagen turnover and connective tissue homeostasis. The rate limiting step of phagocytosis is the binding of specific adhesion receptors, which include the integrins and discoidin domain receptors (DDR), to fibrillar collag...

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Bibliographic Details
Main Authors: Lisa A. Staudinger, Stephen J. Spano, Wilson Lee, Nuno Coelho, Dhaarmini Rajshankar, Michelle P. Bendeck, Tara Moriarty, Christopher A. McCulloch
Format: Article
Language:English
Published: The Company of Biologists 2013-09-01
Series:Biology Open
Subjects:
Cell adhesions
Matrix remodeling
Phagocytosis
Online Access:http://bio.biologists.org/content/2/11/1148

Internet

http://bio.biologists.org/content/2/11/1148

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