In situ vaccination at a peripheral tumor site augments response against melanoma brain metastases

In situ vaccination at a peripheral tumor site augments response against melanoma brain metastases

Background Immune checkpoint inhibition (ICI) alone is not efficacious for a large number of patients with melanoma brain metastases. We previously established an in situ vaccination (ISV) regimen combining radiation and immunocytokine to enhance response to ICIs. Here, we tested whether ISV inhibit...

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Bibliographic Details
Main Authors: Raghava N Sriramaneni, Justin C Jagodinsky, Abigail A Jaquish, Bryce R Anderson, Trang Le, Jonathan A Lubin, Ishan Chakravarty, Ian S Arthur, Clinton M Heinze, Kelsey A Klar, John S Kuo
Format: Article
Language:English
Published: BMJ Publishing Group 2020-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e000809.full

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https://jitc.bmj.com/content/8/2/e000809.full

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