Apoptosis inhibitor of macrophage depletion decreased M1 macrophage accumulation and the incidence of cardiac rupture after myocardial infarction in mice.

Apoptosis inhibitor of macrophage depletion decreased M1 macrophage accumulation and the incidence of cardiac rupture after myocardial infarction in mice.

Cardiac rupture is an important cause of death in the acute phase after myocardial infarction (MI). Macrophages play a pivotal role in cardiac remodeling after MI. Apoptosis inhibitor of macrophage (AIM) is secreted specifically by macrophages and contributes to macrophage accumulation in inflamed t...

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Bibliographic Details
Main Authors: Shohei Ishikawa, Takahisa Noma, Hai Ying Fu, Takashi Matsuzaki, Makoto Ishizawa, Kaori Ishikawa, Kazushi Murakami, Naoki Nishimoto, Akira Nishiyama, Tetsuo Minamino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5679665?pdf=render

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http://europepmc.org/articles/PMC5679665?pdf=render

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