The neuroprotective effects of virally-derived caspase inhibitors p35 and crmA following a necrotic insult

Neuronal excitotoxicity causes energetic impairment and the ensuing cell death has historically been regarded as necrotic. Recent findings, however, indicate that apoptosis may participate in excitotoxicity. Here we examined the neuroprotective mechanisms of the well-characterized viral caspase inhi...

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Bibliographic Details
Main Authors: Madhuri Roy, Robert M Sapolsky
Format: Article
Language:English
Published: Elsevier 2003-10-01
Series:Neurobiology of Disease
Subjects:
p35
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103000834