Interactive effect of age and APOE-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects

Interactive effect of age and APOE-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects

The apolipoprotein E gene (APOE) ε4 allele has a strong and manifold impact on cognition and neuroimaging phenotypes in cognitively normal subjects, including alterations in the white matter (WM) microstructure. Such alterations have often been regarded as a reflection of potential thinning of the m...

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Bibliographic Details
Main Authors: Grégory Operto, José Luis Molinuevo, Raffaele Cacciaglia, Carles Falcon, Anna Brugulat-Serrat, Marc Suárez-Calvet, Oriol Grau-Rivera, Nuria Bargalló, Sebastián Morán, Manel Esteller, Juan Domingo Gispert
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S221315821930333X

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http://www.sciencedirect.com/science/article/pii/S221315821930333X

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