Interactive effect of age and APOE-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects
The apolipoprotein E gene (APOE) ε4 allele has a strong and manifold impact on cognition and neuroimaging phenotypes in cognitively normal subjects, including alterations in the white matter (WM) microstructure. Such alterations have often been regarded as a reflection of potential thinning of the m...
Main Authors: | Grégory Operto, José Luis Molinuevo, Raffaele Cacciaglia, Carles Falcon, Anna Brugulat-Serrat, Marc Suárez-Calvet, Oriol Grau-Rivera, Nuria Bargalló, Sebastián Morán, Manel Esteller, Juan Domingo Gispert |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-01-01
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Series: | NeuroImage: Clinical |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221315821930333X |
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