Learning and memory alterations are associated with hippocampal N-acetylaspartate in a rat model of depression as measured by 1H-MRS.

Learning and memory alterations are associated with hippocampal N-acetylaspartate in a rat model of depression as measured by 1H-MRS.

It is generally accepted that cognitive processes, such as learning and memory, are affected in depression. The present study used a rat model of depression, chronic unpredictable mild stress (CUMS), to determine whether hippocampal volume and neurochemical changes were involved in learning and memo...

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Bibliographic Details
Main Authors: Guangjun Xi, Jiaojie Hui, Zhijun Zhang, Shanshan Liu, Xiangrong Zhang, Gaojun Teng, Kevin C Chan, Ed X Wu, Binbin Nie, Baoci Shan, Lingjiang Li, Gavin P Reynolds
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3237477?pdf=render

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http://europepmc.org/articles/PMC3237477?pdf=render

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