Oxidative stress-induced DNA damage and repair in human peripheral blood mononuclear cells: protective role of hemoglobin.

BACKGROUND:DNA repair is a cellular defence mechanism responding to DNA damage caused in large part by oxidative stress. There is a controversy with regard to the effect of red blood cells on DNA damage and cellular response. AIM:To investigate the effect of red blood cells on H2O2-induced DNA damag...

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Bibliographic Details
Main Authors: Anat Gafter-Gvili, Boris Zingerman, Benaya Rozen-Zvi, Yaacov Ori, Hefziba Green, Ido Lubin, Tsipora Malachi, Uzi Gafter, Michal Herman-Edelstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3706398?pdf=render