Th22 cells as well as Th17 cells expand differentially in patients with early-stage and late-stage myelodysplastic syndrome.

Th22 cells as well as Th17 cells expand differentially in patients with early-stage and late-stage myelodysplastic syndrome.

BACKGROUND: Immunological mechanisms are increasingly recognized in the progression of myelodysplastic syndrome (MDS). Early-stage MDS (E-MDS) is characterized by autoimmune-mediated myelosuppression whereas late-stage MDS (L-MDS) involves immune evasion, giving dysplastic cells growth potential to...

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Bibliographic Details
Main Authors: Lin-lin Shao, Lei Zhang, Yu Hou, Shuang Yu, Xin-guang Liu, Xiao-yang Huang, Yuan-xin Sun, Tian Tian, Na He, Dao-xin Ma, Jun Peng, Ming Hou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3517399?pdf=render

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http://europepmc.org/articles/PMC3517399?pdf=render

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