Liver injury and fibrosis induced by dietary challenge in the Ossabaw miniature Swine.

Liver injury and fibrosis induced by dietary challenge in the Ossabaw miniature Swine.

BACKGROUND:Ossabaw miniature swine when fed a diet high in fructose, saturated fat and cholesterol (NASH diet) develop metabolic syndrome and nonalcoholic steatohepatitis (NASH) characterized by liver injury and fibrosis. This study was conducted to further characterize the development of NASH in th...

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Main Authors: Tiebing Liang, Mouhamad Alloosh, Lauren N Bell, Allison Fullenkamp, Romil Saxena, William Van Alstine, Phelan Bybee, Klára Werling, Michael Sturek, Naga Chalasani, Howard C Masuoka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4433111?pdf=render

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http://europepmc.org/articles/PMC4433111?pdf=render

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