The drug transporter ABCB1 c.3435C>T SNP influences artemether–lumefantrine treatment outcome

The drug transporter ABCB1 c.3435C>T SNP influences artemether–lumefantrine treatment outcome

Abstract Malaria treatment performance is potentially influenced by pharmacogenetic factors. This study reports an association study between the ABCB1 c.3435C>T, CYP3A4*1B (g.-392A>G), CYP3A5*3 (g.6986A>G) SNPs and artemether + lumefantrine treatment outcome in 103 uncomplicated malaria pat...

Full description

Bibliographic Details
Main Authors: Kinanga Kiaco, António Sebastião Rodrigues, Virgílio do Rosário, José Pedro Gil, Dinora Lopes
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Malaria Journal
Subjects:
Human polymorphism
CYP450
MDR1
Artemether–lumefantrine
Angola
Online Access:http://link.springer.com/article/10.1186/s12936-017-2006-6

Internet

http://link.springer.com/article/10.1186/s12936-017-2006-6

Similar Items