ADIPOR1 deficiency-induced suppression of retinal ELOVL2 and docosahexaenoic acid levels during photoreceptor degeneration and visual loss

ADIPOR1 deficiency-induced suppression of retinal ELOVL2 and docosahexaenoic acid levels during photoreceptor degeneration and visual loss

Abstract Lipid metabolism-related gene mutations can cause retinitis pigmentosa, a currently untreatable blinding disease resulting from progressive neurodegeneration of the retina. Here, we demonstrated the influence of adiponectin receptor 1 (ADIPOR1) deficiency in retinal neurodegeneration using...

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Bibliographic Details
Main Authors: Hideto Osada, Eriko Toda, Kohei Homma, Naymel A. Guzman, Norihiro Nagai, Mamoru Ogawa, Kazuno Negishi, Makoto Arita, Kazuo Tsubota, Yoko Ozawa
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03741-5

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https://doi.org/10.1038/s41419-021-03741-5

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