Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer’s Disease Brains

Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer’s Disease Brains

Neuroinflammation is considered a key pathological process in neurodegenerative diseases of aging, including Alzheimer’s disease (AD). Many studies have defined phenotypes of reactive microglia, the brain-resident macrophages, with different antigenic markers to identify those potentially...

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Bibliographic Details
Main Authors: Douglas G. Walker, Tiffany M. Tang, Anarmaa Mendsaikhan, Ikuo Tooyama, Geidy E. Serrano, Lucia I. Sue, Thomas G. Beach, Lih-Fen Lue
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
activation phenotypes
microglia
neuroinflammation
immunohistochemistry
temporal cortex
alzheimer’s disease
amyloid
Online Access:https://www.mdpi.com/1422-0067/21/2/678

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https://www.mdpi.com/1422-0067/21/2/678

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