An innovative diagnostic technology for the codon mutation C580Y in kelch13 of Plasmodium falciparum with MinION nanopore sequencer

An innovative diagnostic technology for the codon mutation C580Y in kelch13 of Plasmodium falciparum with MinION nanopore sequencer

Abstract Background The recent spread of artemisinin (ART)-resistant Plasmodium falciparum represents an emerging global threat to public health. In Southeast Asia, the C580Y mutation of kelch13 (k13) is the dominant mutation of ART-resistant P. falciparum. Therefore, a simple method for the detecti...

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Bibliographic Details
Main Authors: Kazuo Imai, Norihito Tarumoto, Lucky Ronald Runtuwene, Jun Sakai, Kyoko Hayashida, Yuki Eshita, Ryuichiro Maeda, Josef Tuda, Hideaki Ohno, Takashi Murakami, Shigefumi Maesaki, Yutaka Suzuki, Junya Yamagishi, Takuya Maeda
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Malaria Journal
Subjects:
Malaria
Plasmodium falciparum
Artemisinin resistance
LAMP
Nanopore sequencer
MinION™
Online Access:http://link.springer.com/article/10.1186/s12936-018-2362-x

Internet

http://link.springer.com/article/10.1186/s12936-018-2362-x

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