UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression

UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression

Abstract Background Uridine 5′-diphosphate-glucuronosyltransferase 2B (UGT2B) genes code for enzymes that catalyze the clearance of testosterone, dihydrotestosterone (DHT), and DHT metabolites in the prostate basal and luminal tissue. The expression of the UGT2B15, UGT2B17, and UGT2B28 enzymes has n...

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Bibliographic Details
Main Authors: Delores J. Grant, Zinan Chen, Lauren E. Howard, Emily Wiggins, Amanda De Hoedt, Adriana C. Vidal, Skyla T. Carney, Jill Squires, Clara E. Magyar, Jiaoti Huang, Stephen J. Freedland
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Cancer
Subjects:
Prostate cancer
Biochemical recurrence
UDP-glucuronosyltransferases
UGT2B17
Online Access:http://link.springer.com/article/10.1186/s12885-017-3463-6

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http://link.springer.com/article/10.1186/s12885-017-3463-6

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