Whole-body clearing, staining and screening of calcium deposits in the mdx mouse model of Duchenne muscular dystrophy

Abstract Background Duchenne muscular dystrophy (DMD) is a fatal, X-linked genetic disorder. Although DMD is the most common form of muscular dystrophy, only two FDA-approved drugs were developed to delay its progression. In order to assess therapies for treating DMD, several murine models have rece...

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Bibliographic Details
Main Authors: Lukasz Bozycki, Kacper Łukasiewicz, Paweł Matryba, Slawomir Pikula
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Skeletal Muscle
Subjects:
mdx
Online Access:http://link.springer.com/article/10.1186/s13395-018-0168-8