Escape is a more common mechanism than avidity reduction for evasion of CD8+ T cell responses in primary human immunodeficiency virus type 1 infection

<p>Abstract</p> <p>Background</p> <p>CD8+ T cells play an important role in control of viral replication during acute and early human immunodeficiency virus type 1 (HIV-1) infection, contributing to containment of the acute viral burst and establishment of the prognosti...

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Bibliographic Details
Main Authors: Williams Ian, Pellegrino Pierre, Turner Joanna, Wong MaiLee, Wei Xiping, Wang Shuyi, Conrod Karen E, Baalwa Joshua, Turnbull Emma L, Shaw George M, Borrow Persephone
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/8/1/41