O-GlcNAcase expression is sensitive to changes in O-GlcNAc homeostasis

O-linked N-acetylglucosamine (O-GlcNAc) is a post-translational modification involving an attachment of a single β-N-acetylglucosamine moiety to serine or threonine residues in nuclear and cytoplasmic proteins. Cellular O-GlcNAc levels are regulated by two enzymes: O-GlcNAc transferase (OGT) and O-G...

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Bibliographic Details
Main Authors: ZHEN eZHANG, Ee Phie eTan, Nicole eVandenHull, Kenneth R. Peterson, Chad eSlawson
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00206/full