Hypoxic exosomes facilitate bladder tumor growth and development through transferring long non-coding RNA-UCA1

Hypoxic exosomes facilitate bladder tumor growth and development through transferring long non-coding RNA-UCA1

Abstract Background To overcome the hostile hypoxic microenvironment of solid tumors, tumor cells secrete a large number of non-coding RNA-containing exosomes that facilitate tumor development and metastasis. However, the precise mechanisms of tumor cell-derived exosomes during hypoxia are unknown....

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Bibliographic Details
Main Authors: Mei Xue, Wei Chen, An Xiang, Ruiqi Wang, He Chen, Jingjing Pan, Huan Pang, Hongli An, Xiang Wang, Huilian Hou, Xu Li
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Molecular Cancer
Subjects:
Exosomes
LncRNA-UCA1
Hypoxia
Bladder cancer
Online Access:http://link.springer.com/article/10.1186/s12943-017-0714-8

Internet

http://link.springer.com/article/10.1186/s12943-017-0714-8

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