Variable Resistance to Plasminogen Activator Initiated Fibrinolysis for Intermediate-Risk Pulmonary Embolism.

We examine the clinical significance and biomarkers of tissue plasminogen activator (tPA)-catalyzed clot lysis time (CLT) in patients with intermediate-risk pulmonary embolism (PE).Platelet-poor, citrated plasma was obtained from patients with PE. Healthy age- and sex-matched patients served as dise...

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Bibliographic Details
Main Authors: William B Stubblefield, Nathan J Alves, Matthew T Rondina, Jeffrey A Kline
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4751085?pdf=render