Periodic Mechanical Stress Stimulates the FAK Mitogenic Signal in Rat Chondrocytes Through ERK1/2 Activity

Periodic Mechanical Stress Stimulates the FAK Mitogenic Signal in Rat Chondrocytes Through ERK1/2 Activity

Background/Aims: The biological effects of periodic mechanical stress on chondrocytes have been studied extensively over the past few years. However, the mechanisms underlying chondrocyte mechanosensing and signaling in response to periodic mechanical stress remain to be determined. In the current s...

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Bibliographic Details
Main Authors: Wenwei Liang, Kewei Ren, Feng Liu, Weiding Cui, Qing Wang, Zhefeng Chen, Weimin Fan
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Matrix synthesis
FAK
Src
Integrin β1
Periodic mechanical stress
Chondrocyte proliferation
Online Access:http://www.karger.com/Article/FullText/354495

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http://www.karger.com/Article/FullText/354495

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