Crosslinking of CD38 Receptors Triggers Apoptosis of Malignant B Cells

Crosslinking of CD38 Receptors Triggers Apoptosis of Malignant B Cells

Recently, we designed an inventive paradigm in nanomedicine—drug-free macromolecular therapeutics (DFMT). The ability of DFMT to induce apoptosis is based on biorecognition at cell surface, and crosslinking of receptors without the participation of low molecular weight drugs. The system is composed...

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Bibliographic Details
Main Authors: M. Tommy Gambles, Jiahui Li, Jiawei Wang, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
CD38
drug-free macromolecular therapeutics
human serum albumin conjugates
morpholino oligonucleotides
daratumumab
isatuximab
Online Access:https://www.mdpi.com/1420-3049/26/15/4658

Internet

https://www.mdpi.com/1420-3049/26/15/4658

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