Junctional adhesion molecule (JAM)-C deficient C57BL/6 mice develop a severe hydrocephalus.

The junctional adhesion molecule (JAM)-C is a widely expressed adhesion molecule regulating cell adhesion, cell polarity and inflammation. JAM-C expression and function in the central nervous system (CNS) has been poorly characterized to date. Here we show that JAM-C(-/-) mice backcrossed onto the C...

Full description

Bibliographic Details
Main Authors: Lena Wyss, Julia Schäfer, Stefan Liebner, Michel Mittelbronn, Urban Deutsch, Gaby Enzmann, Ralf H Adams, Michel Aurrand-Lions, Karl H Plate, Beat A Imhof, Britta Engelhardt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3445510?pdf=render