An Increase in the Levels of Middle Surface Antigen Characterizes Patients Developing HBV-Driven Liver Cancer Despite Prolonged Virological Suppression

An Increase in the Levels of Middle Surface Antigen Characterizes Patients Developing HBV-Driven Liver Cancer Despite Prolonged Virological Suppression

Hepatitis B virus (HBV) contains three surface glycoproteins—Large-HBs (L-HBs), Middle-HBs (M-HBs), and Small-HBs (S-HBs), known to contribute to HBV-driven pro-oncogenic properties. Here, we examined the kinetics of HBs-isoforms in virologically-suppressed patients who developed or did not develop...

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Bibliographic Details
Main Authors: Giuseppina Brancaccio, Romina Salpini, Lorenzo Piermatteo, Matteo Surdo, Vanessa Fini, Luna Colagrossi, Marco Cantone, Arianna Battisti, Yasunori Oda, Domenico Di Carlo, Francesca Ceccherini-Silberstein, Carlo Federico Perno, Giovanni Battista Gaeta, Valentina Svicher
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Microorganisms
Subjects:
hepatocellular carcinoma
hepatitis B
HBsAg
HBs isoforms
middle-HBs
Online Access:https://www.mdpi.com/2076-2607/9/4/752

Internet

https://www.mdpi.com/2076-2607/9/4/752

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